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Appetite and satiety control in obesity

Obesity affects the regulation of appetite and satiety, often due to hormonal imbalances involving leptin and ghrelin—two key hormones responsible for signaling hunger and fullness. Leptin, which is produced by fat cells, typically suppresses appetite, while ghrelin stimulates it. In individuals with obesity, leptin resistance may occur, diminishing the brain’s response to satiety signals and leading to overeating. Additionally, high levels of ghrelin can persist even after eating, causing continuous hunger. This hormonal disruption can make it challenging to control calorie intake, reinforcing weight gain. Treatment approaches focusing on restoring hormonal balance, such as mindful eating and dietary modifications, may improve appetite control and support long-term weight management.

Committee Members
Speaker at World Obesity and Weight Management Congress 2026 - Russell Rising

Russell Rising

D & S Consulting Services Inc, United States
Speaker at World Obesity and Weight Management Congress 2026 - Robert Gabbay

Robert Gabbay

Harvard Medical School, United States
Speaker at World Obesity and Weight Management Congress 2026 - Hassan Massoud Heshmati

Hassan Massoud Heshmati

Endocrinology Metabolism Consulting, LLC, Hassan Heshmati and Valerie Shaw Endocrine Research, United States
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