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Gut permeability in obesity

Obesity has been linked to an increase in gut permeability, often referred to as "leaky gut." When the intestinal lining becomes compromised, harmful substances like toxins and undigested food particles can leak into the bloodstream, triggering inflammation and an immune response. This chronic inflammation is believed to contribute to insulin resistance and metabolic disorders, further exacerbating obesity and related diseases. Addressing gut permeability involves not only managing body weight but also improving gut health through a balanced diet rich in fiber, prebiotics, and probiotics. Reducing gut inflammation can help improve insulin sensitivity, reduce systemic inflammation, and promote better metabolic function in individuals with obesity.

Committee Members
Speaker at World Obesity and Weight Management Congress 2026 - Russell Rising

Russell Rising

D & S Consulting Services Inc, United States
Speaker at World Obesity and Weight Management Congress 2026 - Robert Gabbay

Robert Gabbay

Harvard Medical School, United States
Speaker at World Obesity and Weight Management Congress 2026 - Hassan Massoud Heshmati

Hassan Massoud Heshmati

Endocrinology Metabolism Consulting, LLC, Hassan Heshmati and Valerie Shaw Endocrine Research, United States
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